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FAIM Opposes Aggregation of Mutant SOD1 That Typifies Some Forms of Familial Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative illness that is unremittingly fatal and for which no effective treatment exists. All forms of ALS are characterized by protein aggregation. In familial forms of ALS, specific and heritable aggregation-prone proteins have been ide...

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Detalles Bibliográficos
Autores principales: Kaku, Hiroaki, Ludlow, Alexander V., Gutknecht, Michael F., Rothstein, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047752/
https://www.ncbi.nlm.nih.gov/pubmed/32153351
http://dx.doi.org/10.3389/fnins.2020.00110