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Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging

Neurocognitive dysfunction is a common postoperative complication, especially in older adult patients. Fingolimod (FTY720) is a sphingosine-1-phosphate receptor modulator that has been found to be neuroprotective in several animal models of central nervous system disease. However, few reports have e...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Xiao, Bin, Li, Chen-Xu, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047799/
https://www.ncbi.nlm.nih.gov/pubmed/31960817
http://dx.doi.org/10.4103/1673-5374.272617