Ox-LDL Causes Endothelial Cell Injury Through ASK1/NLRP3-Mediated Inflammasome Activation via Endoplasmic Reticulum Stress

OBJECTIVE: This study was to investigate the mechanism of inflammatory pathology modification induced by ox-LDL in endothelial cells. METHODOLOGY: In this study, we firstly investigated the efflux of cholesterol of endothelial cells under the treatment of ox-LDL, and cell proliferation, ROS producti...

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Detalles Bibliográficos
Autores principales: Hang, Liwei, Peng, Yan, Xiang, Rui, Li, Xiangdong, Li, Zhiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047838/
https://www.ncbi.nlm.nih.gov/pubmed/32158192
http://dx.doi.org/10.2147/DDDT.S231916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047838/
https://www.ncbi.nlm.nih.gov/pubmed/32158192
http://dx.doi.org/10.2147/DDDT.S231916

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