Cargando…

In situ formation of transcriptional modulators using non-canonical DNA i-motifs

Non-canonical DNA i-motifs and G-quadruplexes are postulated as genetic switches for the transcriptional regulation of proto-oncogenes. However, in comparison to G-quadruplexes, the therapeutic potential of i-motifs is less explored. The development of i-motif selective ligands by conventional appro...

Descripción completa

Detalles Bibliográficos
Autores principales: Saha, Puja, Panda, Deepanjan, Müller, Diana, Maity, Arunabha, Schwalbe, Harald, Dash, Jyotirmayee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047845/
https://www.ncbi.nlm.nih.gov/pubmed/32180928
http://dx.doi.org/10.1039/d0sc00514b