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Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation

BACKGROUND: Currently available short read genome assemblies of the tetraploid protozoan parasite Giardia intestinalis are highly fragmented, highlighting the need for improved genome assemblies at a reasonable cost. Long nanopore reads are well suited to resolve repetitive genomic regions resulting...

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Detalles Bibliográficos
Autores principales: Pollo, Stephen M. J., Reiling, Sarah J., Wit, Janneke, Workentine, Matthew L., Guy, Rebecca A., Batoff, G. William, Yee, Janet, Dixon, Brent R., Wasmuth, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048089/
https://www.ncbi.nlm.nih.gov/pubmed/32111234
http://dx.doi.org/10.1186/s13071-020-3968-8