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A causal modelling framework for reference-based imputation and tipping point analysis in clinical trials with quantitative outcome
We consider estimation in a randomised placebo-controlled or standard-of-care-controlled drug trial with quantitative outcome, where participants who discontinue an investigational treatment are not followed up thereafter, and the estimand follows a treatment policy strategy for handling treatment d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048106/ https://www.ncbi.nlm.nih.gov/pubmed/31718423 http://dx.doi.org/10.1080/10543406.2019.1684308 |