Cargando…
Plasma membrane v-ATPase controls oncogenic Ras-induced macropinocytosis
Oncogenic activation of Ras is associated with the acquisition of a unique set of metabolic dependencies that contribute to tumor cell fitness. Mutant Ras cells are endowed with the capability to internalize and degrade extracellular protein via a fluid–phase uptake mechanism termed macropinocytosis...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048194/ https://www.ncbi.nlm.nih.gov/pubmed/31827278 http://dx.doi.org/10.1038/s41586-019-1831-x |