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Plasma membrane v-ATPase controls oncogenic Ras-induced macropinocytosis
Oncogenic activation of Ras is associated with the acquisition of a unique set of metabolic dependencies that contribute to tumor cell fitness. Mutant Ras cells are endowed with the capability to internalize and degrade extracellular protein via a fluid–phase uptake mechanism termed macropinocytosis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048194/ https://www.ncbi.nlm.nih.gov/pubmed/31827278 http://dx.doi.org/10.1038/s41586-019-1831-x |