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An infectious clone of enterovirus 71(EV71) that is capable of infecting neonatal immune competent mice without adaptive mutations

Enterovirus 71 (EV71) is a major pathogen that causes hand, foot and mouth disease (HFMD), which is a life threatening disease in certain children. The pathogenesis of EV71-caused HFMD is poorly defined due to the lack of simple and robust animal models with severe phenotypes that recapitulate sympt...

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Detalles Bibliográficos
Autores principales: Zhang, Huiying, Song, Zhigang, Zou, Jingyi, Feng, Yanling, Zhang, Jing, Ren, Lehao, Zhang, Xiaonan, Hu, Yunwen, Yuan, Zhenghong, Yi, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048218/
https://www.ncbi.nlm.nih.gov/pubmed/32079505
http://dx.doi.org/10.1080/22221751.2020.1729665