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S100B suppression alters polarization of infiltrating myeloid-derived cells in gliomas and inhibits tumor growth

S100B, a member of the multigene family of Ca(2+)-binding proteins, is overexpressed by most malignant gliomas but its biological role in gliomagenesis is unclear. Recently, we demonstrated that low concentrations of S100B attenuated microglia activation through the induction of STAT3. Furthermore,...

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Detalles Bibliográficos
Autores principales: Gao, Hang, Zhang, Ian Y., Zhang, Leying, Song, Yanyan, Liu, Shunan, Ren, Hui, Liu, Huili, Zhou, Hui, Su, Yanping, Yang, Yihang, Badie, Behnam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048242/
https://www.ncbi.nlm.nih.gov/pubmed/30076898
http://dx.doi.org/10.1016/j.canlet.2018.07.034