Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species‐specific regulation of blood pressure

STK39 encodes a serine threonine kinase, SPAK, which is part of a multi‐kinase network that determines renal Na(+) reabsorption and blood pressure (BP) through regulation of sodium‐chloride co‐transporters in the kidney. Variants within STK39 are associated with susceptibility to essential hypertens...

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Detalles Bibliográficos
Autores principales: Mercado, Carlo J., Wang, Xiaochun, Grimm, Paul R., Welling, Paul A., Chang, Yen‐Pei C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048380/
https://www.ncbi.nlm.nih.gov/pubmed/32109341
http://dx.doi.org/10.14814/phy2.14379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048380/
https://www.ncbi.nlm.nih.gov/pubmed/32109341
http://dx.doi.org/10.14814/phy2.14379

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