Cargando…
Identification and characterization of alternative STK39 transcripts within human and mouse kidneys reveals species‐specific regulation of blood pressure
STK39 encodes a serine threonine kinase, SPAK, which is part of a multi‐kinase network that determines renal Na(+) reabsorption and blood pressure (BP) through regulation of sodium‐chloride co‐transporters in the kidney. Variants within STK39 are associated with susceptibility to essential hypertens...
Autores principales: | Mercado, Carlo J., Wang, Xiaochun, Grimm, Paul R., Welling, Paul A., Chang, Yen‐Pei C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048380/ https://www.ncbi.nlm.nih.gov/pubmed/32109341 http://dx.doi.org/10.14814/phy2.14379 |
Ejemplares similares
-
STK39, overexpressed in osteosarcoma, regulates osteosarcoma cell invasion and proliferation
por: Huang, Tao, et al.
Publicado: (2017) -
STK39 and WNK1 Are Potential Hypertension Susceptibility Genes in the BELHYPGEN Cohort
por: Persu, Alexandre, et al.
Publicado: (2016) -
STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression
por: Cunnington, Michael S, et al.
Publicado: (2009) -
STK39 Polymorphism Is Associated with Essential Hypertension: A Systematic Review and Meta-Analysis
por: Xi, Bo, et al.
Publicado: (2013) -
STK39 enhances the progression of Cholangiocarcinoma via PI3K/AKT pathway
por: Hao, Xiaopei, et al.
Publicado: (2021)