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Large-scale cell-type-specific imaging of protein synthesis in a vertebrate brain

Despite advances in methods to detect protein synthesis, it has not been possible to measure endogenous protein synthesis levels in vivo in an entire vertebrate brain. We developed a transgenic zebrafish line that allows for cell-type-specific labeling and imaging of nascent proteins in the entire a...

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Detalles Bibliográficos
Autores principales: Shahar, Or David, Schuman, Erin Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048392/
https://www.ncbi.nlm.nih.gov/pubmed/32091983
http://dx.doi.org/10.7554/eLife.50564