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The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children
Wilms tumor is the most common pediatric malignancy in the kidney. The miR34b/c is a downstream target gene of the transcription factor p53. The important role of TP53 mutations, the methylation of miR34b/c, and the interaction between these two molecules in tumorigenesis have been well documented....
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048686/ https://www.ncbi.nlm.nih.gov/pubmed/32083300 http://dx.doi.org/10.1042/BSR20194202 |