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The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children

Wilms tumor is the most common pediatric malignancy in the kidney. The miR34b/c is a downstream target gene of the transcription factor p53. The important role of TP53 mutations, the methylation of miR34b/c, and the interaction between these two molecules in tumorigenesis have been well documented....

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Detalles Bibliográficos
Autores principales:	Wang, Juxiang, Lou, Susu, Huang, Xiaokai, Mo, Yixiao, Wang, Zhen, Zhu, Jinhong, Tian, Xiaoqian, Shi, Jiandong, Zhou, Haixia, He, Jing, Ruan, Jichen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Diagnostics & Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048686/ https://www.ncbi.nlm.nih.gov/pubmed/32083300 http://dx.doi.org/10.1042/BSR20194202

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