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Longitudinal DNA methylation differences precede type 1 diabetes

DNA methylation may be involved in development of type 1 diabetes (T1D), but previous epigenome-wide association studies were conducted among cases with clinically diagnosed diabetes. Using multiple pre-disease peripheral blood samples on the Illumina 450 K and EPIC platforms, we investigated longit...

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Detalles Bibliográficos
Autores principales: Johnson, Randi K., Vanderlinden, Lauren A., Dong, Fran, Carry, Patrick M., Seifert, Jennifer, Waugh, Kathleen, Shorrosh, Hanan, Fingerlin, Tasha, Frohnert, Brigitte I., Yang, Ivana V., Kechris, Katerina, Rewers, Marian, Norris, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048736/
https://www.ncbi.nlm.nih.gov/pubmed/32111940
http://dx.doi.org/10.1038/s41598-020-60758-0