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Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration

0.5–1% of ALS (Amyotrophic Lateral Sclerosis) and Parkinson's disease (PD) are associated with mutations in the angiogenin (ANG). These mutations are thought to cause disease through a loss of ANG function, but this hypothesis has not been evaluated statistically. In addition, the potential for...

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Detalles Bibliográficos
Autores principales: Aluri, Krishna C., Salisbury, Joseph P., Prehn, Jochen H. M., Agar, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048737/
https://www.ncbi.nlm.nih.gov/pubmed/32111867
http://dx.doi.org/10.1038/s41598-020-60431-6