Genetic and pharmacological inhibition of inflammasomes reduces the survival of Mycobacterium tuberculosis strains in macrophages

Mycobacterium tuberculosis infection causes high rates of morbidity and mortality. Host-directed therapy may enhance the immune response, reduce tissue damage and shorten treatment duration. The inflammasome is integral to innate immune responses but over-activation has been described in tuberculosi...

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Detalles Bibliográficos
Autores principales: Subbarao, Sathyavani, Sanchez-Garrido, Julia, Krishnan, Nitya, Shenoy, Avinash R., Robertson, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048741/
https://www.ncbi.nlm.nih.gov/pubmed/32111888
http://dx.doi.org/10.1038/s41598-020-60560-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048741/
https://www.ncbi.nlm.nih.gov/pubmed/32111888
http://dx.doi.org/10.1038/s41598-020-60560-y

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