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Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure

Heart failure is a major public health problem affecting over 23 million people worldwide. In this study, we present the results of a large scale meta-analysis of heart failure GWAS and replication in a comparable sized cohort to identify one known and two novel loci associated with heart failure. H...

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Detalles Bibliográficos
Autores principales: Arvanitis, Marios, Tampakakis, Emmanouil, Zhang, Yanxiao, Wang, Wei, Auton, Adam, Dutta, Diptavo, Glavaris, Stephanie, Keramati, Ali, Chatterjee, Nilanjan, Chi, Neil C., Ren, Bing, Post, Wendy S., Battle, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048760/
https://www.ncbi.nlm.nih.gov/pubmed/32111823
http://dx.doi.org/10.1038/s41467-020-14843-7