Cargando…
Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure
Heart failure is a major public health problem affecting over 23 million people worldwide. In this study, we present the results of a large scale meta-analysis of heart failure GWAS and replication in a comparable sized cohort to identify one known and two novel loci associated with heart failure. H...
Autores principales: | Arvanitis, Marios, Tampakakis, Emmanouil, Zhang, Yanxiao, Wang, Wei, Auton, Adam, Dutta, Diptavo, Glavaris, Stephanie, Keramati, Ali, Chatterjee, Nilanjan, Chi, Neil C., Ren, Bing, Post, Wendy S., Battle, Alexis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048760/ https://www.ncbi.nlm.nih.gov/pubmed/32111823 http://dx.doi.org/10.1038/s41467-020-14843-7 |
Ejemplares similares
-
Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood
por: Dutta, Diptavo, et al.
Publicado: (2022) -
Redefining tissue specificity of genetic regulation of gene expression in the presence of allelic heterogeneity
por: Arvanitis, Marios, et al.
Publicado: (2022) -
Change of guard at ACTN
por: Hoke, Ahmet
Publicado: (2023) -
Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
por: Ratnapriya, Rinki, et al.
Publicado: (2019) -
Rare Genetic Variants Associated With Myocardial Fibrosis: Multi-Ethnic Study of Atherosclerosis
por: Shabani, Mahsima, et al.
Publicado: (2022)