Asc-1 Transporter (SLC7A10): Homology Models And Molecular Dynamics Insights Into The First Steps Of The Transport Mechanism

The alanine-serine-cysteine transporter Asc-1 regulates the synaptic availability of d-serine and glycine (the two co-agonists of the NMDA receptor) and is regarded as an important drug target. To shuttle the substrate from the extracellular space to the cytoplasm, this transporter undergoes multipl...

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Detalles Bibliográficos
Autores principales: Mikou, Afaf, Cabayé, Alexandre, Goupil, Anne, Bertrand, Hugues-Olivier, Mothet, Jean-Pierre, Acher, Francine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048771/
https://www.ncbi.nlm.nih.gov/pubmed/32111919
http://dx.doi.org/10.1038/s41598-020-60617-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048771/
https://www.ncbi.nlm.nih.gov/pubmed/32111919
http://dx.doi.org/10.1038/s41598-020-60617-y

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