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Asc-1 Transporter (SLC7A10): Homology Models And Molecular Dynamics Insights Into The First Steps Of The Transport Mechanism
The alanine-serine-cysteine transporter Asc-1 regulates the synaptic availability of d-serine and glycine (the two co-agonists of the NMDA receptor) and is regarded as an important drug target. To shuttle the substrate from the extracellular space to the cytoplasm, this transporter undergoes multipl...
Autores principales: | Mikou, Afaf, Cabayé, Alexandre, Goupil, Anne, Bertrand, Hugues-Olivier, Mothet, Jean-Pierre, Acher, Francine C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048771/ https://www.ncbi.nlm.nih.gov/pubmed/32111919 http://dx.doi.org/10.1038/s41598-020-60617-y |
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