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The GEF Cytohesin-2/ARNO Mediates Resistin induced Phenotypic Switching in Vascular Smooth Muscle Cells

The pro-inflammatory adipokine resistin induces a phenotypic switch of vascular smooth muscle cells (VSMC), a process decisive for atherosclerosis, including morphological changes, increased synthetic activity, proliferation and migration. The guanine-exchange factor ARNO (Cytohesin-2) has been show...

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Detalles Bibliográficos
Autores principales: Heun, Yvonn, Gräff, Pascal, Lagara, Aikaterini, Schelhorn, Romina, Mettler, Ramona, Pohl, Ulrich, Mannell, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048779/
https://www.ncbi.nlm.nih.gov/pubmed/32111889
http://dx.doi.org/10.1038/s41598-020-60446-z