Cargando…

miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells

Elevation of the levels of reactive oxygen species (ROS) is a major tissue-degenerative phenomenon involved in aging and aging-related diseases. The detailed mechanisms underlying aging-related ROS generation remain unclear. Presently, the expression of microRNA (miR)-142-5p was significantly upregu...

Descripción completa

Detalles Bibliográficos
Autores principales: Houri, Kei, Mori, Tatsufumi, Onodera, Yuta, Tsujimoto, Takatoshi, Takehara, Toshiyuki, Nakao, Shinichi, Teramura, Takeshi, Fukuda, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048811/
https://www.ncbi.nlm.nih.gov/pubmed/32111926
http://dx.doi.org/10.1038/s41598-020-60346-2