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miR-142 induces accumulation of reactive oxygen species (ROS) by inhibiting pexophagy in aged bone marrow mesenchymal stem cells
Elevation of the levels of reactive oxygen species (ROS) is a major tissue-degenerative phenomenon involved in aging and aging-related diseases. The detailed mechanisms underlying aging-related ROS generation remain unclear. Presently, the expression of microRNA (miR)-142-5p was significantly upregu...
Autores principales: | Houri, Kei, Mori, Tatsufumi, Onodera, Yuta, Tsujimoto, Takatoshi, Takehara, Toshiyuki, Nakao, Shinichi, Teramura, Takeshi, Fukuda, Kanji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048811/ https://www.ncbi.nlm.nih.gov/pubmed/32111926 http://dx.doi.org/10.1038/s41598-020-60346-2 |
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