Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

The interaction between immune cells and phosphatidylserine (PS) molecules exposed on the surface of apoptotic-tumor bodies, such as those induced by chemotherapies, contributes to the formation of an immunosuppressive tumor microenvironment (TME). Annexin A5 (AnxA5) binds with high affinity to PS e...

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Detalles Bibliográficos
Autores principales: Kang, Tae Heung, Park, Jung Hwa, Yang, Andrew, Park, Hyun Jin, Lee, Sung Eun, Kim, Young Seob, Jang, Gun-Young, Farmer, Emily, Lam, Brandon, Park, Yeong-Min, Hung, Chien-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048819/
https://www.ncbi.nlm.nih.gov/pubmed/32111835
http://dx.doi.org/10.1038/s41467-020-14821-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048819/
https://www.ncbi.nlm.nih.gov/pubmed/32111835
http://dx.doi.org/10.1038/s41467-020-14821-z

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