Cargando…

Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment

The interaction between immune cells and phosphatidylserine (PS) molecules exposed on the surface of apoptotic-tumor bodies, such as those induced by chemotherapies, contributes to the formation of an immunosuppressive tumor microenvironment (TME). Annexin A5 (AnxA5) binds with high affinity to PS e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Tae Heung, Park, Jung Hwa, Yang, Andrew, Park, Hyun Jin, Lee, Sung Eun, Kim, Young Seob, Jang, Gun-Young, Farmer, Emily, Lam, Brandon, Park, Yeong-Min, Hung, Chien-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048819/ https://www.ncbi.nlm.nih.gov/pubmed/32111835 http://dx.doi.org/10.1038/s41467-020-14821-z

Ejemplares similares

TLR9 acts as a sensor for tumor-released DNA to modulate anti-tumor immunity after chemotherapy
por: Kang, Tae Heung, et al.
Publicado: (2019)

Repositioning of the antipsychotic drug TFP for sepsis treatment
por: Park, Jung Hwa, et al.
Publicado: (2019)

A novel TLR4 binding protein, 40S ribosomal protein S3, has potential utility as an adjuvant in a dendritic cell-based vaccine
por: Park, Hyun Jin, et al.
Publicado: (2019)

Interactions between tumor-derived proteins and Toll-like receptors
por: Jang, Gun-Young, et al.
Publicado: (2020)

The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation
por: Jeong, Sun Young, et al.
Publicado: (2023)

Sequential Treatment with an Immune Checkpoint Inhibitor Followed by a Small-Molecule Targeted Agent Increases Drug-Induced Pneumonitis
por: Jung, Jongheon, et al.
Publicado: (2021)

Immune checkpoint silencing using RNAi-incorporated nanoparticles enhances antitumor immunity and therapeutic efficacy compared with antibody-based approaches
por: Won, Ji Eun, et al.
Publicado: (2022)

Mycobacterium abscessus ᴅ-alanyl-ᴅ-alanine dipeptidase induces the maturation of dendritic cells and promotes Th1-biased immunity
por: Lee, Seung Jun, et al.
Publicado: (2016)

The immune landscape of high-grade brain tumor after treatment with immune checkpoint blockade
por: Park, Jang Hyun, et al.
Publicado: (2022)

Homing of annexin-labeled stem cells to apoptotic cells
por: Gerasimou, Argyrios, et al.
Publicado: (2008)

Novel, genetically induced mouse model that recapitulates the histological morphology and immunosuppressive tumor microenvironment of metastatic peritoneal carcinomatosis
por: Tseng, Ssu-Hsueh, et al.
Publicado: (2020)

Laser-Based Strategies to Treat Diabetic Macular Edema: History and New Promising Therapies
por: Park, Young Gun, et al.
Publicado: (2014)

Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells
por: Ham, Seok Won, et al.
Publicado: (2023)

Role of Annexin A5 on Mitochondria-Dependent Apoptosis Induced by Tetramethoxystilbene in Human Breast Cancer Cells
por: Hong, Mihye, et al.
Publicado: (2014)

Annexin A1 in plasma from patients with bronchial asthma: its association with lung function
por: Lee, Sun-Hye, et al.
Publicado: (2018)

Highly crystalline and uniform conjugated polymer thin films by a water-based biphasic dip-coating technique minimizing the use of halogenated solvents for transistor applications
por: Kwon, Eun Hye, et al.
Publicado: (2019)

Impact of Personal Protective Equipment on Out-of-Hospital Cardiac Arrest Resuscitation in Coronavirus Pandemic
por: Ko, Hye-Young, et al.
Publicado: (2021)

The annexins
por: Moss, Stephen E, et al.
Publicado: (2004)

Neoagarohexaose-mediated activation of dendritic cells via Toll-like receptor 4 leads to stimulation of natural killer cells and enhancement of antitumor immunity
por: Lee, Moon Hee, et al.
Publicado: (2017)

Improvement of Nanostructured Polythiophene Film Uniformity Using a Cruciform Electrode and Substrate Rotation in Atmospheric Pressure Plasma Polymerization
por: Kim, Jae Young, et al.
Publicado: (2021)

Soluble immune checkpoint molecules in patients with antineutrophil cytoplasmic antibody-associated vasculitis
por: Pyo, Jung Yoon, et al.
Publicado: (2022)

A Review of Plasma Synthesis Methods for Polymer Films and Nanoparticles under Atmospheric Pressure Conditions
por: Jang, Hyo Jun, et al.
Publicado: (2021)

Peripheral lymphocyte count as a surrogate marker of immune checkpoint inhibitor therapy outcomes in patients with non-small-cell lung cancer
por: Lee, Ye Jin, et al.
Publicado: (2022)

A Quenched Annexin V‐Fluorophore for the Real‐Time Fluorescence Imaging of Apoptotic Processes In Vitro and In Vivo
por: Kim, Hyunjin, et al.
Publicado: (2020)

Nanoparticle-Based Vaccine Delivery for Cancer Immunotherapy
por: Park, Yeong-Min, et al.
Publicado: (2013)

Annexins in Glaucoma
por: Yap, Timothy E., et al.
Publicado: (2018)

Clinical Significance of Annexin A1 Expression in Breast Cancer
por: Yom, Cha Kyong, et al.
Publicado: (2011)

Interaction of annexin A6 with alpha actinin in cardiomyocytes
por: Mishra, Sumita, et al.
Publicado: (2011)

Prognostic significance of annexin A2 and annexin A4 expression in patients with cervical cancer
por: Choi, Chel Hun, et al.
Publicado: (2016)

Annexin-1 regulated by HAUSP is essential for UV-induced damage response
por: Park, J-J, et al.
Publicado: (2015)

Dependency of Tunneling-Magnetoresistance Ratio on Nanoscale Spacer Thickness and Material for Double MgO Based Perpendicular-Magnetic-Tunneling-Junction
por: Lee, Du-Yeong, et al.
Publicado: (2016)

Home blood pressure monitoring: a position statement from the Korean Society of Hypertension Home Blood Pressure Forum
por: Ihm, Sang-Hyun, et al.
Publicado: (2022)

SQUARE GRID DEFORMATION ANALYSIS OF THE MACULA AND POSTOPERATIVE METAMORPHOPSIA AFTER MACULAR HOLE SURGERY
por: Park, Sun Ho, et al.
Publicado: (2021)

Homing-Associated Cell Adhesion Molecules and Cell Cycle Status on the Nucleated Cells in the Bone Marrow, Mobilized Peripheral Blood and Cord Blood
por: Lee, Young-Ho, et al.
Publicado: (2004)

Synthesis and Properties of Plasma-Polymerized Methyl Methacrylate via the Atmospheric Pressure Plasma Polymerization Technique
por: Park, Choon-Sang, et al.
Publicado: (2019)

Synthesis and Properties of Thiophene and Aniline Copolymer Using Atmospheric Pressure Plasma Jets Copolymerization Technique
por: Jang, Hyo Jun, et al.
Publicado: (2020)

Efficacy of immune checkpoint inhibitors according to PD‐L1 tumor proportion scores in non‐small cell lung cancer
por: Park, Seongho, et al.
Publicado: (2019)

Annexin A2 Acts as an Adhesion Molecule on the Endometrial Epithelium during Implantation in Mice
por: Wang, Bing, et al.
Publicado: (2015)

Development of an Atmospheric Pressure Plasma Jet Device Using Four-Bore Tubing and Its Applications of In-Liquid Material Decomposition and Solution Plasma Polymerization
por: Bae, Gyu Tae, et al.
Publicado: (2022)

Endoplasmic reticulum stress enhances the antigen-specific T cell immune responses and therapeutic antitumor effects generated by therapeutic HPV vaccines
por: Lee, Sung Yong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m24vgc8fgmjmqbpiss9j8jkcd0