Dynamic CpG methylation delineates subregions within super-enhancers selectively decommissioned at the exit from naive pluripotency

Clusters of enhancers, referred as to super-enhancers (SEs), control the expression of cell identity genes. The organisation of these clusters, and how they are remodelled upon developmental transitions remain poorly understood. Here, we report the existence of two types of enhancer units within SEs...

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Detalles Bibliográficos
Autores principales: Bell, Emma, Curry, Edward W., Megchelenbrink, Wout, Jouneau, Luc, Brochard, Vincent, Tomaz, Rute A., Mau, King Hang T., Atlasi, Yaser, de Souza, Roshni A., Marks, Hendrik, Stunnenberg, Hendrik G., Jouneau, Alice, Azuara, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048827/
https://www.ncbi.nlm.nih.gov/pubmed/32111830
http://dx.doi.org/10.1038/s41467-020-14916-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048827/
https://www.ncbi.nlm.nih.gov/pubmed/32111830
http://dx.doi.org/10.1038/s41467-020-14916-7

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