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Genomic alterations and abnormal expression of APE2 in multiple cancers

Although APE2 plays essential roles in base excision repair and ATR-Chk1 DNA damage response (DDR) pathways, it remains unknown how the APE2 gene is altered in the human genome and whether APE2 is differentially expressed in cancer patients. Here, we report multiple-cancer analyses of APE2 genomic a...

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Detalles Bibliográficos
Autores principales: Jensen, Katherine A., Shi, Xinghua, Yan, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048847/
https://www.ncbi.nlm.nih.gov/pubmed/32111912
http://dx.doi.org/10.1038/s41598-020-60656-5