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Metformin Delays the Development of Atherosclerosis in Type 1 Diabetes Mellitus via the Methylglyoxal Pathway

INTRODUCTION: The aim of our study was to determine the effect of metformin administration on juvenile type 1 diabetes mellitus and atherosclerosis in apolipoprotein E null (ApoE(−/−)) mice and to explore the mechanism involved. METHODS: Eighteen male ApoE(−/−) mice were injected with streptozotocin...

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Detalles Bibliográficos
Autores principales: Liu, Aihong, Li, Kailin, Xu, Linlin, Si, Min, Teng, Guoxin, Li, Guimei, Xue, Jiang, Liang, Shuang, Song, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048885/
https://www.ncbi.nlm.nih.gov/pubmed/31955370
http://dx.doi.org/10.1007/s13300-020-00761-w