GFAT1/HBP/O-GlcNAcylation Axis Regulates β-Catenin Activity to Promote Pancreatic Cancer Aggressiveness

Reprogrammed glucose and glutamine metabolism are essential for tumor initiation and development. As a branch of glucose and metabolism, the hexosamine biosynthesis pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) and contributes to the O-GlcNAcylation process. However, t...

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Detalles Bibliográficos
Autores principales: Jia, Chunzeng, Li, Hengchao, Fu, Deliang, Lan, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048922/
https://www.ncbi.nlm.nih.gov/pubmed/32149084
http://dx.doi.org/10.1155/2020/1921609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048922/
https://www.ncbi.nlm.nih.gov/pubmed/32149084
http://dx.doi.org/10.1155/2020/1921609

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