Biguanides Induce Acute de novo Lipogenesis in Human Primary Sebocytes

INTRODUCTION: Acne arises during puberty, in part, due to elevated hormones and growth factors which stimulate de novo lipogenesis (DNL) in primary sebocytes to significantly increase sebum production. Oral isotretinoin is an effective acne therapy, reducing sebum production through inducing apoptos...

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Detalles Bibliográficos
Autores principales: Nicoll, James, Buehrer, Benjamin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048953/
https://www.ncbi.nlm.nih.gov/pubmed/32158247
http://dx.doi.org/10.2147/CCID.S243154