Biguanides Induce Acute de novo Lipogenesis in Human Primary Sebocytes
INTRODUCTION: Acne arises during puberty, in part, due to elevated hormones and growth factors which stimulate de novo lipogenesis (DNL) in primary sebocytes to significantly increase sebum production. Oral isotretinoin is an effective acne therapy, reducing sebum production through inducing apoptos...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048953/ https://www.ncbi.nlm.nih.gov/pubmed/32158247 http://dx.doi.org/10.2147/CCID.S243154 |