Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization

The transcription factor Sox10 is a key regulator in the fate determination of a subpopulation of multipotent trunk neural crest (NC) progenitors toward glial cells instead of sensory neurons in the dorsal root ganglia (DRG). However, the mechanism by which Sox10 regulates glial cell fate commitment...

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Detalles Bibliográficos
Autores principales: Liu, Jessica Aijia, Tai, Andrew, Hong, Jialin, Cheung, May Pui Lai, Sham, Mai Har, Cheah, Kathryn S. E., Cheung, Chi Wai, Cheung, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049171/
https://www.ncbi.nlm.nih.gov/pubmed/32029586
http://dx.doi.org/10.1073/pnas.1916164117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049171/
https://www.ncbi.nlm.nih.gov/pubmed/32029586
http://dx.doi.org/10.1073/pnas.1916164117

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