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Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization
The transcription factor Sox10 is a key regulator in the fate determination of a subpopulation of multipotent trunk neural crest (NC) progenitors toward glial cells instead of sensory neurons in the dorsal root ganglia (DRG). However, the mechanism by which Sox10 regulates glial cell fate commitment...
Autores principales: | Liu, Jessica Aijia, Tai, Andrew, Hong, Jialin, Cheung, May Pui Lai, Sham, Mai Har, Cheah, Kathryn S. E., Cheung, Chi Wai, Cheung, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049171/ https://www.ncbi.nlm.nih.gov/pubmed/32029586 http://dx.doi.org/10.1073/pnas.1916164117 |
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