Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα

BACKGROUND: Ubiquitin-fold modifier-1 (Ufm1) is a recently identified ubiquitin-like protein. We previously confirmed that Ufm1 expression was increased in diabetic mice. However, its role in the development of diabetes remains undefined. METHODS: Lentivirus-mediated gene knockdown and overexpressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xiaolei, Zhang, Hengyan, Zhuang, Langen, Jin, Guoxi, Yang, Qingqing, Li, Min, Sun, Weihua, Chen, Fengling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049273/
https://www.ncbi.nlm.nih.gov/pubmed/32158197
http://dx.doi.org/10.2147/DDDT.S238695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049273/
https://www.ncbi.nlm.nih.gov/pubmed/32158197
http://dx.doi.org/10.2147/DDDT.S238695

Ejemplares similares