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Geniposide Balances the Redox Signaling to Mediate Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells

PURPOSE: To investigate the effect of geniposide on the biosynthesis of insulin and the expression protein disulfide isomerase (PDI) and endoplasmic reticulum oxidoreductin 1 (ERO1) in the presence of low (5 mM) and high (25 mM) glucose in pancreatic β cells. METHODS: The content of insulin was meas...

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Detalles Bibliográficos
Autores principales: Liu, Chunyan, Hao, Yanan, Yin, Fei, Liu, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049278/
https://www.ncbi.nlm.nih.gov/pubmed/32158246
http://dx.doi.org/10.2147/DMSO.S240794