The novel Isatin analog KS99 targets stemness markers in acute myeloid leukemia

Leukemic stem cells are multipotent, self-renewing, highly proliferative cells that can withstand drug treatments. Although currently available treatments potentially destroy blast cells, they fail to eradicate leukemic progenitor cells completely. Aldehyde dehydrogenase and STAT3 are frequently up-...

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Detalles Bibliográficos
Autores principales: Annageldiyev, Charyguly, Gowda, Krishne, Patel, Trupti, Bhattacharya, Priyanjali, Tan, Su-Fern, Iyer, Soumya, Desai, Dhimant, Dovat, Sinisa, Feith, David J., Loughran, Thomas P., Amin, Shantu, Claxton, David, Sharma, Arati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049373/
https://www.ncbi.nlm.nih.gov/pubmed/31123028
http://dx.doi.org/10.3324/haematol.2018.212886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049373/
https://www.ncbi.nlm.nih.gov/pubmed/31123028
http://dx.doi.org/10.3324/haematol.2018.212886

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