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Doxorubicin inhibits miR-140 expression and upregulates PD-L1 expression in HCT116 cells, opposite to its effects on MDA-MB-231 cells

One of the most challenging problems in colorectal cancer (CRC) is resistance to chemotherapy drugs such as doxorubicin (DOX). The programmed death ligand-1 (PD-L1) is related to chemoresistance and is overexpressed in several human cancer cell types. Here, we investigated the changes in the express...

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Detalles Bibliográficos
Autores principales: NABA, Noel Mopouguini, TOLAY, Nazife, ERMAN, Batu, SAYI YAZGAN, Ayca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049454/
https://www.ncbi.nlm.nih.gov/pubmed/32123492
http://dx.doi.org/10.3906/biy-1909-12