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Hypoxia induced changes in miRNAs and their target mRNAs in extracellular vesicles of esophageal squamous cancer cells

BACKGROUND: Extracellular vesicles (EVs) are endogenous membrane vesicles with a diameter of 30–200 nm. It has been reported that hypoxic cancer cells can release numerous EVs to mediate multiple regional and systemic effects in the tumor microenvironment. METHODS: In this study, we used ultracentri...

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Detalles Bibliográficos
Autores principales: Chen, Fangyu, Chu, Li, Li, Jie, Shi, Yu, Xu, Bing, Gu, Junjie, Yao, Xijuan, Tian, Meng, Yang, Xi, Sun, Xinchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049507/
https://www.ncbi.nlm.nih.gov/pubmed/31922357
http://dx.doi.org/10.1111/1759-7714.13295