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Re-defining T-Cell Exhaustion: Subset, Function, and Regulation

Acute viral infection or vaccination generates highly functional memory CD8 T cells following the Ag resolution. In contrast, persistent antigenic stimulation in chronic viral infection and cancer leads to a state of T-cell dysfunction termed T-cell exhaustion. We and other have recently identified...

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Detalles Bibliográficos
Autores principales: Im, Se Jin, Ha, Sang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049579/
https://www.ncbi.nlm.nih.gov/pubmed/32158590
http://dx.doi.org/10.4110/in.2020.20.e2