Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity

The T cell co-stimulatory molecule OX40 and its cognate ligand OX40L have attracted broad research interest as a therapeutic target in T cell-mediated diseases. Accumulating preclinical evidence highlights the therapeutic efficacy of both agonist and blockade of the OX40–OX40L interaction. Despite t...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Lin, Qing, Zhang, Zhirong, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049610/
https://www.ncbi.nlm.nih.gov/pubmed/32140389
http://dx.doi.org/10.1016/j.apsb.2019.08.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049610/
https://www.ncbi.nlm.nih.gov/pubmed/32140389
http://dx.doi.org/10.1016/j.apsb.2019.08.010

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