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Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity
The T cell co-stimulatory molecule OX40 and its cognate ligand OX40L have attracted broad research interest as a therapeutic target in T cell-mediated diseases. Accumulating preclinical evidence highlights the therapeutic efficacy of both agonist and blockade of the OX40–OX40L interaction. Despite t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049610/ https://www.ncbi.nlm.nih.gov/pubmed/32140389 http://dx.doi.org/10.1016/j.apsb.2019.08.010 |