Novel small molecule retrograde transport blocker confers post-exposure protection against ricin intoxication

Ricin is a highly toxic type 2 ribosome-inactivating protein (RIP) which is extracted from the seeds of castor beans. Ricin is considered a potential bioterror agent and no effective antidote for ricin exists so far. In this study, by structural modification of a retrograde transport blocker Retro-2...

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Detalles Bibliográficos
Autores principales: Zhao, Xu, Li, Haixia, Li, Jia, Liu, Kunlu, Wang, Bo, Wang, Yuxia, Li, Xingzhou, Zhong, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049615/
https://www.ncbi.nlm.nih.gov/pubmed/32140395
http://dx.doi.org/10.1016/j.apsb.2019.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049615/
https://www.ncbi.nlm.nih.gov/pubmed/32140395
http://dx.doi.org/10.1016/j.apsb.2019.08.005

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