The C-terminal tail of the yeast mitochondrial transcription factor Mtf1 coordinates template strand alignment, DNA scrunching and timely transition into elongation

Mitochondrial RNA polymerases depend on initiation factors, such as TFB2M in humans and Mtf1 in yeast Saccharomyces cerevisiae, for promoter-specific transcription. These factors drive the melting of promoter DNA, but how they support RNA priming and growth was not understood. We show that the flexi...

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Detalles Bibliográficos
Autores principales: Basu, Urmimala, Lee, Seung-Won, Deshpande, Aishwarya, Shen, Jiayu, Sohn, Byeong-Kwon, Cho, Hayoon, Kim, Hajin, Patel, Smita S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049685/
https://www.ncbi.nlm.nih.gov/pubmed/31980825
http://dx.doi.org/10.1093/nar/gkaa040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049685/
https://www.ncbi.nlm.nih.gov/pubmed/31980825
http://dx.doi.org/10.1093/nar/gkaa040

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