Uncovering tissue-specific binding features from differential deep learning

Transcription factors (TFs) can bind DNA in a cooperative manner, enabling a mutual increase in occupancy. Through this type of interaction, alternative binding sites can be preferentially bound in different tissues to regulate tissue-specific expression programmes. Recently, deep learning models ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Phuycharoen, Mike, Zarrineh, Peyman, Bridoux, Laure, Amin, Shilu, Losa, Marta, Chen, Ke, Bobola, Nicoletta, Rattray, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049686/
https://www.ncbi.nlm.nih.gov/pubmed/31974574
http://dx.doi.org/10.1093/nar/gkaa009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049686/
https://www.ncbi.nlm.nih.gov/pubmed/31974574
http://dx.doi.org/10.1093/nar/gkaa009

Ejemplares similares