DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends

The cellular response to DNA double-strand breaks (DSBs) is initiated by the Mre11–Rad50–Xrs2 (MRX) complex that has structural and catalytic functions. MRX association at DSBs is counteracted by Rif2, which is known to interact with Rap1 that binds telomeric DNA through two tandem Myb-like domains....

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Detalles Bibliográficos
Autores principales: Bonetti, Diego, Rinaldi, Carlo, Vertemara, Jacopo, Notaro, Marco, Pizzul, Paolo, Tisi, Renata, Zampella, Giuseppe, Longhese, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049697/
https://www.ncbi.nlm.nih.gov/pubmed/31879780
http://dx.doi.org/10.1093/nar/gkz1203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049697/
https://www.ncbi.nlm.nih.gov/pubmed/31879780
http://dx.doi.org/10.1093/nar/gkz1203

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