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Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom

Eukaryotic protein synthesis generally initiates at a start codon defined by an AUG and its surrounding Kozak sequence context, but the quantitative importance of this context in different species is unclear. We tested this concept in two pathogenic Cryptococcus yeast species by genome-wide mapping...

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Detalles Bibliográficos
Autores principales: Wallace, Edward W J, Maufrais, Corinne, Sales-Lee, Jade, Tuck, Laura R, de Oliveira, Luciana, Feuerbach, Frank, Moyrand, Frédérique, Natarajan, Prashanthi, Madhani, Hiten D, Janbon, Guilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049704/
https://www.ncbi.nlm.nih.gov/pubmed/32020195
http://dx.doi.org/10.1093/nar/gkaa060