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Biphasic unbinding of a metalloregulator from DNA for transcription (de)repression in Live Bacteria

Microorganisms use zinc-sensing regulators to alter gene expression in response to changes in the availability of zinc, an essential micronutrient. Under zinc-replete conditions, the Fur-family metalloregulator Zur binds to DNA tightly in its metallated repressor form to Zur box operator sites, repr...

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Detalles Bibliográficos
Autores principales: Jung, Won, Sengupta, Kushal, Wendel, Brian M, Helmann, John D, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049717/
https://www.ncbi.nlm.nih.gov/pubmed/32009151
http://dx.doi.org/10.1093/nar/gkaa056