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Biphasic unbinding of a metalloregulator from DNA for transcription (de)repression in Live Bacteria
Microorganisms use zinc-sensing regulators to alter gene expression in response to changes in the availability of zinc, an essential micronutrient. Under zinc-replete conditions, the Fur-family metalloregulator Zur binds to DNA tightly in its metallated repressor form to Zur box operator sites, repr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049717/ https://www.ncbi.nlm.nih.gov/pubmed/32009151 http://dx.doi.org/10.1093/nar/gkaa056 |