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Generation of pre-tRNAs from polycistronic operons is the essential function of RNase P in Escherichia coli

Ribonuclease P (RNase P) is essential for the 5′-end maturation of tRNAs in all kingdoms of life. In Escherichia coli, temperature sensitive mutations in either its protein (rnpA49) and or RNA (rnpB709) subunits lead to inviability at nonpermissive temperatures. Using the rnpA49 temperature sensitiv...

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Detalles Bibliográficos
Autores principales: Mohanty, Bijoy K, Agrawal, Ankit, Kushner, Sidney R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049720/
https://www.ncbi.nlm.nih.gov/pubmed/31993626
http://dx.doi.org/10.1093/nar/gkz1188